Wilson received rave reviews for her role in Mike Nichols '2003 HBO drama mini-series Angels in America. He received both a Golden Globe nomination and an Emmy nomination for Best Supporting Actor. He had his first star billing movie role when he was cast as Brad Adamson in Todd Field's Little Children Kate Winslet opposite.
Wilson was playing Nite Owl II / Turn Dan Berg of Zack Snyder's 2009 film adaptation of the graphic novel Watchmen. This film reunited with his Wilson Little Children co-star Jackie Earle Haley.He played the primary antagonist Lynch in 2010, The A-Team and co-stars Rose Byrne in James Wan's thriller insidious.
